SOFIA

The Problem: ADHD Treatment Adherence

Attention-Deficit/Hyperactivity Disorder (ADHD) affects approximately 11% of children in the United States.

Despite being one of the most treatable psychiatric conditions, ADHD has low long-term treatment adherence, with rates dropping to less than 20% after the first year.

Common barriers to adherence include:

Forgetfulness and lack of routine follow-through
Complexity of treatment, including stimulant medication schedules and side effects
Misconceptions about ADHD and its treatment, including doubts about medication effectiveness

The challenge is not treatment availability – it is sustained adherence and informed support at home.

What is SOFIA?

SOFIA is a text-based support program designed to help parents manage and support their child’s ADHD treatment journey.

Targeted at parents of children aged 6-12 who are newly prescribed stimulant medication, SOFIA provides timely, structured SMS-based guidance to improve adherence and overall treatment experience.

The program delivers:

Educational content addressing misconceptions about ADHD and medication
Interactive prompts (e.g., true/false, Q&A) to reinforce understanding
Practical tools to support school, home life, and social development
Adaptive messaging based on user behavior and prescription refill patterns

SOFIA extends care beyond the clinical setting – supporting families in managing ADHD in everyday life.

Outcomes

SOFIA has demonstrated:

Improved medication adherence
- 85% or participants in the SMS program refilled prescriptions on time, compared to 62% receiving standard care
Effective support for behavior and treatment management
- Ongoing messaging helped parents better manage routines, school engagement, and daily challenges
Increased understanding of ADHD and treatment
- Interactive content addressed misconceptions and reinforced key knowledge over time
Personalized engagement through adaptive messaging
- Messaging tailored to refill behavior and user interaction supported sustained participation

The Team

SOFIA was co-created by:

Dr. Joseph Biederman
- Chief of the Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD
- Director, Alan and Lorraine Bressler Clinical and Research Program for Autism Spectrum Disorders, Massachusetts General Hospital
- Professor of Psychiatry, Harvard Medical School
MEMOTEXT Corporation

Resources

Publications

An innovative SMS intervention to improve adherence to stimulants in children with ADHD: Preliminary findings

Interested?

Message us to get a demo or to learn more about the program.

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