Press Release – OBIO X A4i
Press Release OBIO® support A4i to expand Canadian presence through new partnership with Waypoint Centre for Mental Health Care June 12, 2025 The collaboration enhances A4i’s footprint across health systems, supporting digital innovation in severe mental illness June 12, 2025 (Toronto, Ontario) – Among patients with complex behavioural and mental health conditions, 23% face re-hospitalization […]
Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-Management and Provider Engagement: Protocol for a Feasibility Trial
This study describes the protocol for a feasibility trial evaluating App4Independence (A4i), a digital health platform designed to improve illness self-management and treatment engagement among individuals with schizophrenia spectrum disorders. The planned study used a single-blind randomized design, with participants assigned to either A4i or a control condition and followed for six months. Feasibility measures included recruitment and […]
Predicting symptom response and engagement in a digital intervention among individuals with schizophrenia and related psychoses
This study examined whether machine learning could predict individual responses to and engagement with a smartphone-based digital intervention among people with schizophrenia and related psychotic disorders. Researchers used data from an earlier open trial involving 38 participants with psychosis, primarily schizophrenia spectrum disorders, who used the App4Independence (A4i) psychosocial smartphone intervention for one month. Machine learning models incorporated […]
Feasibility and outcomes of a multi-function mobile health approach for the schizophrenia spectrum: App4Independence (A4i)
The study examined the feasibility of A4i, a multi-feature mobile health application designed to support illness self-management among people with schizophrenia spectrum and other psychotic disorders. The study took place in a large urban Canadian centre, with 38 participants using A4i for approximately one month. A pre-post study design was used to assess medication adherence, personal […]
A4i

A4i (App4Indpendence) is a platform for supporting people with complex behavioural and mental health conditions. Currently, A4i is being used to support the recovery processes in psychosis and schizophrenia, and newly in opioid use disorders.